E-ISSN 2587-0831
Original Article
Breast Cancer in Turkey; An Analysis of 20.000 Patients with Breast Cancer
1 Department of Surgery, İstanbul University İstanbul School of Medicine, İstanbul, Turkey  
2 Department of Surgery, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Florida, USA  
3 Department of Surgery, Akdeniz University School of Medicine, Antalya, Turkey  
Eur J Breast Health 2019; 15: 141-146
DOI: 10.5152/ejbh.2019.4890
Key Words: Breast cancer, demography, reproductive functions, pathology, survival, Turkey


Objective: Breast cancer is the most common type of cancer and the leading cause of cancer-related deaths in women in Turkey. This study presents the characteristics of patients registered in National Breast Cancer Registry Program of Turkish Federation of Breast Diseases Societies.


Materials and Methods: The registry contains 242 variables under 10 categories and 699 questions.  Patients were recorded (online and offline) from nationwide breast centers around Turkey.


Results: Twenty-thousand patients were registered between May 2005 and April 2017 at 36 centers. After data cleaning, 19,503 women were included in the study. The median age at diagnosis was 51 [14-97]; 17.2% were younger than 40 and 37.2% were premenopausal; 13.6% were nulliparous. Breast conserving surgery rate was 39.3%. Histopathology was invasive ductal cancer in 77%. Majority of patients had stage II cancer (48.3%). Estrogen, progesterone and HER-2 receptor positivity rates in invasive breast cancer were 72.5%, 62.5% and 21.8%, respectively. The mean tumor diameter was 2.5±1.7 cm.  During the mean 51.6 months of follow-up, the local/regional and systemic recurrence rates were 3.7% and 5.2%, respectively; five and 10-year overall survival rates were 86% and 76%.


Conclusion: Despite increasing number of screening centers and free-of-charge mammography (ages 40 to 69) and mobile screening systems in recent years, a significant portion of patients were diagnosed at advanced stage due to lack of breast cancer awareness. In contrast with the study published 5 years ago, there was a decrease in the rate of pre-menopausal women and an increase in the breast conserving surgery.



Cite this article as: Özmen V, Özmen T, Doğru V. Breast Cancer in Turkey; An Analysis of 20.000 Patients with Breast Cancer. Eur J Breast Health 2019; 15(3): 141-146.

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AVES | Copyright © 2019 Turkish Federation of Breast Diseases Associations | Latest Update: 01.10.2019